Immunogenicity and Immunosensitivity of a Guinea Pig B-Cell Leukemia Subline Lacking Cell Surface la Antigens
نویسندگان
چکیده
L2C is a transplantable B-cell leukemia of strain 2 guinea pigs. Transplantation protection experiments were performed with L2C sublines expressing or lacking cell surface antigens coded for by the I region of the major histocompatibility complex (la). A subline (BZ-L2C) that lacked cell surface la antigens was immunogenic but relatively resistant to immunological attack. The data suggest that rejection of this B-cell leukemia may be influenced by expression of cell surface la antigens.
منابع مشابه
Immunogenicity and immunosensitivity of a guinea pig B-cell leukemia subline lacking cell surface Ia antigens.
L2C is a transplantable B-cell leukemia of strain 2 guinea pigs. Transplantation protection experiments were performed with L2C sublines expressing or lacking cell surface antigens coded for by the I region of the major histocompatibility complex (Ia). A subline (BZ-L2C) that lacked cell surface Ia antigens was immunogenic but relatively resistant to immunological attack. The data suggest that ...
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